其他產(chǎn)品及廠家
cvt-12012 is an orally bioavailable inhibitor of stearoyl-coa desaturase (scd; ic50 = 6.1 nm in hepg2 cells).
更新時間:2025-06-07
biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropeptidase-i and with less neurotoxicity.
更新時間:2025-06-07
bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous t cell lymphoma (ctcl).
更新時間:2025-06-07
beta-lapachone is a specific dna topoisomerase i inhibitor, and no inhibitory activities against dna topoisomerase ii or ligase.
更新時間:2025-06-07
besifloxacin hcl is a fourth-generation fluoroquinolone antibiotic.
更新時間:2025-06-07
bepotastine is a non-sedating and selective h1 receptor antagonist (pic50: 5.7).
更新時間:2025-06-07
baf312 (siponimod), a next-generation s1p receptor modulator, is specific for s1p1 and s1p5 receptors with ec50 of 0.39 nm and 0.98 nm,respectively. the specificity of baf312 for s1p1 and s1p5 receptors exhibits >1000-fold over s1p2, s1p3 and s1p4 recepto
更新時間:2025-06-07
azomycin is an antimicrobial antibiotic produced by a strain of nocardia mesenterica.
更新時間:2025-06-07
azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
更新時間:2025-06-07
azd3514 is a potent and oral androgen receptor downregulator with ki of 2.2 μm and has ability of reducing ar protein expression.phase 1.
更新時間:2025-06-07
azd1981 is an effective and specific crth2 (dp2) receptor antagonist (ic50: 4 nm), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including dp1. azd1981 has been used in trials studying the treatment and basic science of as
更新時間:2025-06-07
azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
更新時間:2025-06-07
atracurium besylate is a non-depolarizing neuromuscular blocking agent with short duration of action. its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alterna
更新時間:2025-06-07
at101, the r-(-) enantiomer of gossypol acetic acid, binds with bcl-2, bcl-xl and mcl-1 with ki of 0.32 μm, 0.48 μm and 0.18 μm; does not inhibit bir3 domain and bid. phase 2.
更新時間:2025-06-07
astragaloside a (astragaloside iv) is the primary pure saponin isolated from astragalus membranaceus, which has been widely used for the therapy of cardiovascular diseases.
更新時間:2025-06-07
as-604850 is a specific and atp-competitive pi3kγ inhibitor (ic50: 250 nm), 18-fold more selective for pi3kγ than pi3kα, and over 80-fold selectivity for pi3kγ than pi3kδ/β.
更新時間:2025-06-07
arq 621 is an allosteric, and selective eg5 mitotic motor protein inhibitor. phase 1.
更新時間:2025-06-07
apocynin is a specific nadph-oxidase inhibitor (ic50: 10 μm).
更新時間:2025-06-07
anagrelide hydrochloride(bl4162a) is a drug used for the treatment of essential thrombocytosis.
更新時間:2025-06-07
anacardic acid is an effective inhibitor of p300 and p300/cbp-associated factor histone acetyltranferases. it also has antimicrobial activity, antibacterial activity, and inhibits prostaglandin synthase, lipoxygenase, and tyrosinase.
更新時間:2025-06-07
amprenavir is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (hiv) protease.
更新時間:2025-06-07
ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
更新時間:2025-06-07
ampicillin sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. ampicillin sodium inhibits bacterial cell wall synthesis by binding to penicillin binding proteins, thereby inhibiting peptidoglycan syn
更新時間:2025-06-07
amoxicillin sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
更新時間:2025-06-07
ammonium glycyrrhizinate inhibits the cytopathology and growth of several unrelated dna/rna viruses.
更新時間:2025-06-07
amikacin sulfate(bay416651 sulfate) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin a.
更新時間:2025-06-07
amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
更新時間:2025-06-07
amg 900 is a potent and highly selective pan-aurora kinases inhibitor for aurora a/b/c with ic50 of 5 nm/4 nm /1 nm. it is >10-fold selective for aurora kinases than p38α, tyk2, jnk2, met and tie2. phase 1.
更新時間:2025-06-07
enalaprilat（ic50=1.94 nm） is a potent angiotensin-converting enzyme (ace) inhibitor.
更新時間:2025-06-07
ag14361 is an effective inhibitor of parp1 (ki<5 nm).
更新時間:2025-06-07
repsox is a potent and selective of the tgfβr-1/alk5 inhibitor.
更新時間:2025-06-07
amonafide(as1413) produces protein-associated dna-strand breaks through a topoisomerase ii-mediated reaction, but does not produce topoisomerase i-mediated dna cleavage.
更新時間:2025-06-07
tie2 kinase inhibitor， an optimized compound of sb-203580, is selective to tie2 with ic50 of 0.25 μm, which is 200-fold more effective than p38.
更新時間:2025-06-07
mln4924 is an effective and specific small molecule nedd8-activating enzyme (nae) inhibitor (ic50: 4.7 nm).
更新時間:2025-06-07
ast-1306 is a novel irreversible inhibitor of egfr and erbb2 with ic50 of 0.5 nm and 3 nm, respectively.
更新時間:2025-06-07
ino-1001 is an effective inhibitor of parp (ic50<50 nm in cho cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
更新時間:2025-06-07
tubacin is a highly potent and selective, reversible, cell-permeable hdac6 inhibitor with an ic50 of 4 nm, approximately 350-fold selectivity over hdac1.
更新時間:2025-06-07
bms-345541 is a highly selective inhibitor of the catalytic subunits of ikk-2 and ikk-1 with ic50 of 0.3 μm and 4 μm, respectively.
更新時間:2025-06-07
pci-34051 is an effective and selective hdac8 inhibitor (ic50: 10 nm).
更新時間:2025-06-07
bix02188 is a specific mek5 inhibitor (ic50: 4.3 nm), also inhibits erk5 catalytic activity (ic50: 810 nm), and does not inhibit closely related kinases mek1/2, jnk2, and erk2.
更新時間:2025-06-07
oligomycin a is an inhibitor of atp synthase, inhibits oxidative phosphorylation and all the atp-dependent processes occurring on the coupling membrane of mitochondria.
更新時間:2025-06-07
copanlisib is a phosphoinositide 3-kinase (pi3k) inhibitor with potential antineoplastic activity. copanlisib inhibits the activation of the pi3k signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell
更新時間:2025-06-07
gdc-0879 is a novel, potent and selective b-raf inhibitor with ic50 of 0.13 nm with activity against c-raf as well.
更新時間:2025-06-07
osi-027 is a selective and potent dual inhibitor of mtorc1 and mtorc2 with ic50 of 22 nm and 65 nm, and more than 100-fold selectivity observed for mtor than pi3kα, pi3kβ, pi3kγ or dna-pk. phase 1.
更新時間:2025-06-07
calcitriol is the physiologically active form of vitamin d. it is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (calcifediol). its production is stimulated by low blood calcium levels and parathyroid hormone. calci
更新時間:2025-06-07
go 6983 is a pan-pkc inhibitor against for pkcα, pkcβ, pkcγ, pkcδ and pkcζ with ic50 of 7 nm, 7 nm, 6 nm, 10 nm and 60 nm, respectively.
更新時間:2025-06-07
bafetinib (inno-406) is an effective and specific dual bcr-abl/lyn inhibitor (ic50: 5.8/19 nm), and no inhibition of the phosphorylation of the t315i mutant and less effective to c-kit and pdgfr.
更新時間:2025-06-07
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